2024

Bogdan R, Roark K, Saxena A, Mitchell C, Hailey M, Staley S, Nagarkatti P, Nagarkatti M, Busbee PB. Aryl hydrocarbon receptor ligand supplementation impacts colitis-associated depressive-like behavior. American Association of Immunologists. Chicago, IL, May 3-7, 2024.

Bogdan R, Roark K, Saxena A, Mitchell C, Hailey M, Staley S, Nagarkatti P, Nagarkatti M, Busbee PB. Aryl hydrocarbon receptor ligand supplementation impacts colitis-associated depressive-like behavior. USC Discover Day, Columbia, SC, April 25, 2024. (graduate student poster winner)

2023

Saxena, A., Mitchell, C., Staley, S., Bogdan, R., Roark, K., Hailey, M., Nagarkatti, M., Nagarkatti, P.S, Busbee, P.B. Aryl hydrocarbon receptor regulates genes in colonic epithelial cells to mitigate colitis severity in the DSS-induced murine model. American Association of Immunologists. Washington DC, May 11-15, 2023.

Mitchell, C., Saxena, A., Hailey, M., Roark, K., Bogdon, R., Staley, S., Nagarkatti, M., Nagarkatti, P.S, Busbee, P.B. Investigation of the aryl hydrocarbon receptor’s role in colitis as it relates to observed disease-specific sex differences. American Association of Immunologists. Washington DC, May 11-15, 2023.

Staley, S., Davis, K., Pena, M., Nagarkatti, M., Nagarkatti, P., Busbee, P.B. Role of Bacteroides acidifaciens in gut inflammation during colitis. American Association of Immunologists. Washington DC, May 11-15, 2023.

Bogdon, R., Roark, K., Saxena, A., Mitchell, C., Hailey, M., Staley, S., Busbee, P.B. Depressive-like behavior associated with colitis is altered after treatment with aryl hydrocarbon receptor ligand. American Association of Immunologists. Washington DC, May 11-15, 2023.

Staley, S., Nagarkatti, M., Nagarkatti, P.S, Busbee, P.B. Role of gram-negative bacterial species Bacteroides acidifaciens (BA) in the promotion and/or progression of colitis. Discover Day USC, Columbia, SC, April 21, 2023. (graduate student poster winner)

Saxena, A., Mitchell, C., Staley, S., Bogdan, R., Roark, K., Hailey, M., Nagarkatti, M., Nagarkatti, P.S, Busbee, P.B. I3C alleviate ulcerative colitis by improving intestinal epithelial barrier function via AhR/IL-22 pathway in Colonic epithelial cells. Discover Day USC, Columbia, SC, April 21, 2023. (postdoctoral poster winner - 2nd place)

Mitchell, C., Busbee, P.B. Investigation of the role of aryl hydrocarbon receptor in colitis and disease-associated sex differences. Discover Day USC, Columbia, SC, April 21, 2023.

2022

Saxena A., Mitchell C., Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti, P, Busbee P.B. AhR Expression of Vil1-expressing colonic epithelial cells is essential for I3C-mediated protection against colitis. American Association of Immunologists. Portland, OR. May 06-10, 2022.

Staley S., Busbee P.B. The role and regulation of Bacteroides acidifaciens during colitis. 2022 UofSC Discover Day, Columbia, SC. April 22, 2022.

Saxena A., Mitchell C., Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti, P, Busbee P.B. I3C-Mediated protection against colitis dependent on AhR expression on Vil1-expressing colonic epithelial cells. 2022 UofSC Discover Day, Columbia, SC. April 22, 2022.

Mitchell C., Saxena A., Staley S., Hailey M., Nagarkatti P., Nagarkatti M., Busbee P.B. Role of AhR in Sex Differences Observed in Colitis. 2022 UofSC Discover Day, Columbia, SC. April 22, 2022.

Mitchell C., Staley S., Saxena A., Wilson K., Nagarkatti M., Nagarkatti P., Busbee P.B. AhR expression on rorc-expressing immune cells is essential for I3C-mediated protection against colitis and IL-22 production by ILC3s. South Carolina Academy of Sciences (SCAS) annual meeting. Aiken, SC. April 2, 2022.

Staley S., Nagarkatti M., Nagarkatti P., Busbee P.B. The role and regulation of Bacteroides acidifaciens during colitis. South Carolina Academy of Sciences (SCAS) annual meeting. Aiken, SC. April 2, 2022.

Saxena A., Mitchell C., Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti, P, Busbee P.B. AhR expression of Vil1-expressing colonic epithelial cells is essential for I3C-mediated protection against colitis. Congress of Crohn’s and Colitis. VIRTUAL. January 20-22, 2022.

2021

Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti P., and Busbee P.B. Dependency of the aryl hydrocarbon receptor in indole-3-carbinol-mediated attenuation of colitis and prevention of colitis-associated microbial dysbiosis. STEMNoire Inaugural Research and Holistic Wellness Conference. Virtual Meeting. June 24-26, 2021.

Mitchell C., Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti P., and Busbee P.B. Ahr expression on Vil1-expressing colonic epithelial cells are essential for I3C-mediated protection against colitis. 2021 UofSC Discover Day, Virtual Meeting, April 23, 2021.

Williams M.C., Staley S., Mitchell C., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti P., and Busbee P.B. Ahr expresssion on Rorc-expressing immune cells is essential for I3C-medicated protection against colitis. 2021 UofSC Discover Day, Virtual Meeting, April 23, 2021.

Mitchell C., Staley S., Wilson K., Rutkovsky A., Wisniewski P.J., Dopkins N., Nagarkatti M., Nagarkatti P., and Busbee P.B. AhR expression on both Rorc-specific immune cells and Vil1-expressing colonic epithelial cells are essential for I3C-mediated protection against colitis. American Association of Immunologist (AAI) annual meeting. Virtual Meeting. May 10th-15th, 2021. Selected for AAI platform presentation and travel award

2020

Busbee P.B, Wilson K, Nagarkatti M, Nagarkatti P. Indole-3-carbinol prevents colitis and regulates microbial dysbiosis by induction of anti-microbial peptides and mucins in an IL-22 dependent manner. American Association of Immunologist (AAI) annual meeting. Honolulu, HA. May 8th-12th, 2020.

Busbee PB. Role and Regulation of the AhR-IL22 Axis in 13C-Mediated Protection Against Colitis. Annual NIH Center for Dietary Supplements and Inflammation COBRE EAC Meeting. Virtual. February 12th, 2020.

2019

Busbee PB, Alrafas H, Dopkins N, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol prevents murine colitis development via an IL-22-dependent mechanism that regulates anti-microbial peptides and mucus production. Annual National Meeting of American Association of Immunologists. San Diego, CA. May 9-13th, 2019. AAI Trainee Abstract Award Winner and selected for platform presentation

Busbee PB, Alrafas H, Dopkins N, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol prevents murine colitis development via an IL-22-dependent mechanism that regulates anti-microbial peptides and mucus production. USC Discovery Day. Columbia, SC. April 26th, 2019. 1st Place Postdoctoral Poster Award

Busbee PB, Alrafas H, Dopkins N, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol prevents murine colitis development via an IL-22-dependent mechanism that regulates anti-microbial peptides and mucus production. Annual CAM/COBRE EAC Meeting. Columbia, SC. March 28, 2019.

2018

Busbee PB, Menzel L, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms by regulating the release of colonic anti-microbial peptides which prevents disease-associated microbial dysbiosis. Annual CAM/COBRE EAC Meeting. Columbia, SC. May 17th, 2018.

Busbee PB, Menzel L, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms by regulating the release of colonic anti-microbial peptides which prevents disease-associated microbial dysbiosis. Annual National Meeting of American Association of Immunologists. Austin, TX. May 4-8th, 2018.

Busbee PB, Menzel L, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms by regulating the release of colonic anti-microbial peptides which prevents disease-associated microbial dysbiosis. USC Discovery Day. Columbia, SC. April 20th, 2018.

2017

Busbee PB, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms through alterations in gut microbial composition and metabolomic pathways, particularly through decreasing disease-associated Bacteroides acidifaciens species. Annual National Meeting of American Association of Immunologists. Washington, D.C. May 12-16th, 2017. AAI Trainee Abstract Award Winner and selected for platform presentation

Busbee PB, Nagarkatti M, and Nagarkatti PS. Alterations in p53 expression in PBMCs of PTSD patients leads to dysregulation in miRNA biogenesis which promotes an inflammatory Th17 immune cell phenotype. Annual National Meeting of American Association of Immunologists. Washington, D.C. May 12-16th, 2017.

Busbee PB, Menzel L, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms through alterations in gut microbial composition and metabolomic pathways, particularly through increasing butyrate-producing bacteria. USC Discovery Day. Columbia, SC. April 21st, 2017. 2ndPlace Postdoctoral Poster Award

2016

Busbee PB, Nagarkatti M, and Nagarkatti PS. Natural dietary indole, indole-3-carbinol, prevents gut microbiota dysbiosis during murine TNBS colitis induction, effectively alleviating colitis associated symptoms. International Congress of Immunologists. Melbourne, Australia. August 21-26th, 2016.

Busbee PB, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol ameliorates murine colitis symptoms through alterations in gut microbial composition by restoring Firmicute-associated species and decreasing colitis-associated Bacteriodetes species. Annual National Meeting of Society of Toxicology. New Orleans, LA. March 13-17th, 2016.

2015

Busbee PB, Nagarkatti M, and Nagarkatti PS. Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, attenuate staphylococcal entertoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis. Annual National Meeting of American Association of Immunologists. New Orleans, LA. May 8-12th, 2015.

2013

Busbee PB, Nagarkatti M, and Nagarkatti PS. Indole-3-carbinol and 3,3’-diindolylmethane decrease histone deacetylase 3 which plays an important role in the promotion of staphylococcal entertoxin B-induced immune cell activation. Annual National Meeting of Society of Toxicology. San Antonio, TX. March 10-14th, 2013.

2012

Busbee PB, Nagarkatti M, and Nagarkatti PS. Anti-inflammatory properties exhibited by aryl hydrocarbon receptor (AhR) ligands, indole-3-carbinol and 3,3’-diindolylmethane, during staphylococcal enterotoxin B-induced immune system activation. Annual National Meeting of Society of Toxicology. San Francisco, CA. March 11-15th, 2012. Selected for platform presentation